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Estrace is an estrogen drug that has a feminizing effect on the body, stimulates the need of the vagina, the uterus, the fallopian tubes, the mammary gland and channels, the incisions and pigmentation in the genitals, the formation of other female sexual habits (fat distribution, etc.); growth and closure of long bone epiphyses. Estrace contributes to regular bleeding endometriosis, endometrial hyperplasia causes high concentrations, inhibits bone resorption, induces the fibrinogen synthesis. Increase in blood concentrations of thyroxine, iron, copper, etc. has a prokoagulant effect on the blood, increases the synthesis of vitamin K-dependent conglomerate of the factors (2, 7, 9, 10) in the liver, reduces the amount of antithrombin 3. These evidence on how to use their estrogen insufficiency during menopause and after gynecological surgery, ovariotomy, girls, puberty delay, alopecia for provocation by hyperandrogenemia, in the case of polycystic ovarian syndrome, hirsutism, uterine persistence, on the first mulieress of the gallbladder, uterine bleeding, postcital contraception, mulieress prevents migraine and osteoporosis during menopause, men and mulieress breast cancer with metastases (palliative treatment), prostate cancer (palliative treatment). Dosage and administration: Estrace is given orally without chewing, with a small amount of water, as a mass of 2 milligrams per day for 21 days, then a break for the next 7 days and after treatment is re-established. The duration of treatment is up to 6 months. Women with uterus, removing or female postmenopausal treatment can be treated every day. When the normalized menstrual cycle and are retained with on-board reception, cyclums 5 start (1 hour menstruiss cycle = 1 day).